In which she looks straight into the camera and tells the audience "I am not a witch. I'm nothing you've heard. I am you."
The last part of that line clearly references some of the unflattering information that has come to light in the last few weeks about O'Donnell, including inconsistencies in what she has said about her education and her personal and business financial problems.
In an effort to make herself accessible O'Donnell says, "None of us are perfect."
Tea Party backed candidate then transitions in the ad to her core message that change is needed in Washington.
"None of us can be happy with what we see all around us. Politicians who think spending, trading favors and back-room deals are the ways to stay in office."
She finishes the ad vowing to "...go to Washington and do what you'd do. I'm Christine O'Donnell, and I approved this message. I'm you."
The ad, which was taped last week, begins airing Tuesday morning statewide, a source with knowledge of the ad strategy tells CNN. Because Delaware doesn't have its own television market campaigns have to buy time in Philadelphia and Salisbury, Maryland to cover the state. While refusing to disclose an exact amount, the source says it is a "substantial buy."
National Republicans had criticized the O'Donnell campaign for waiting this long to go up with paid advertising since it had raised more than two million dollars since her upset victory last month in the primary over Rep. Mike Castle.
When asked whether more ads would run this week, the source said they "could very well."